Our lens probes, custom designed for in vivo imaging with nVista, enable you to visualize Ca2+ activity in hundreds of neurons in the striatum in freely behaving rodents. Study movement planning, reward circuitry, decision-making and more!
https://www.youtube.com/watch?v=qqcQWBQ626w
Given the importance of striatal activity for movement, nVista is ideal for assessing striatal function during freely moving behavioral assays. The patterning of activity within the striatum has proven quite amenable to Ca2+ imaging and has allowed us to analyze activity patterns across the various striatal cell types and regions in completely novel ways.
Description
Animal Model: Mouse Brain Area: Nucleus Accumbens Indicator: GCaMP6 Notes: Ca2+ transients in mice expressing GCaMP6 in nucleus accumbens MSNs during reward learning in Med Associates operant conditioning chambers. Courtesy Of: Jones Parker, Pfizer Neuroscience Research Unit